Research lines
Find out the main topics of the interdisciplinary research areas we work in, and the projects that support them
NEUROREGENERATION & NEUROREHABILITATON
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Signaling and OMICs (transcriptomics, proteomics, microbiomics)
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Neuronal differentiation, neuritogenic mechanisms, neurotrophic factors
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Spinal cord injury (biomarkers, gene and cell therapies, determinants of rehabilitation)
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New biomaterials for neuroregeneration
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Electrical stimulation for neuroregeneration
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Neurodegeneration (e.g. Alzheimer’s disease)
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Basic to Clinical Research
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Projects:
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GoBack - 'New therapeutic targets for spinal cord regeneration' (PTDC/CVT-CVT/32261/2017 and CENTRO-01-0145-FEDER-032261)
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Proteomics in SCI - 'Proteomic profiling of serum and cerebrospinal fluid to identify candidate biomarkers of Spinal Cord Injury severity and prognosis' (EPIC-XS-0000379): epic-xs.eu
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ProTmedula - 'Temporal profile of regeneration markers in samples from patients with spinal cord injury', in MEDISIS (CENTRO-01-0246-FEDER-000018)
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SCIMBIONT - 'Spinal Cord Injury Rehabilitation: Gut dysbiosis and immune biomarkers as functional prognosis tools and new therapeutic targets', in MEDISIS (CENTRO-01-0246-FEDER-000018)
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NeuroStimSpinal - 'A step forward to spinal cord injury repair using innovative stimulated nanoengineered scaffolds' (EU FETOPEN G.A. No: 829060)
OSTEOREGENERATION & MUSCULOSKELETAL REHABILITATON
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Biomaterials: chemical, physical and topographic cues
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Doped ceramics and other biomaterials, dental prostheses
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Instrumented active bone prostheses (sensors, actuators)
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Electrical stimulation for osteoregeneration
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Fractures, Osteoporosis, Vertebral pathologies
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Basic to Clinical Research
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Projects:
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STIMULUS - 'In-vitro evaluation of stimulation methods for bone regeneration around orthopaedic implants' (EXPL/EMS-SIS/2128/2013)
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PPBI bioimaging (PPBI-POCI-01-0145-FEDER-02212)
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FLEXOBONE - 'Flexoelectricity for engineering osteoinductive electromechanical transducers' (FCT 2022.02424.PTDC)
PROTEOSTASIS IN AGING AND DISEASES
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Aging and Proteostasis in cardiovascular and nervous systems
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Proteostasis in Hypertension and Heart failure
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Proteostasis in Spinal cord injury and Alzheimer’s disease
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New chemicals for detection and disaggregation of protein and lipid aggregates
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Pharming new anti-hypertensive peptides
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Basic and Clinical Research
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Projects:
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'The impact of viral infections on the development of neurodegenerative diseases: investigation of cellular and molecular mechanisms' (colaboration between Brazilian Universities and UAveiro)
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pAGE - 'Protein Aggregation across the lifespan' (CENTRO-01-0145-FEDER-000003)
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Exercise intervention in heart failure (POCI-01-0145-FEDER-030011)
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LipidPro (Prove it 2ª Ed UA/CampusTEC/Centro2020)
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F'Marker (P2020, nº 17351, 17/SI/2015), Angelini Award (2012/2013 AUA!, 4º Ed)
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ProTmedula/MEDISIS (CENTRO-01-0246-FEDER-000018)​
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EPIC-XS - 'Are Exosomes Mediating the Positive Effects of Exercise Training in Patient with Heart Failure?' (EPIC-XS-0000219)